Abstract: The WENO5M scheme is modified to simulate the chemical reacting flow based on a novel uncoupled method for chemical nonequilibrium flow. For validating the new implementation, several benchmarks have been tested. The Oran's shock induced detonation experiment has been simulated first. The influences of different chemical reaction mechanisms and grid convergence have been considered and the results compare well with those from experiments. The second test case is the 2d H₂/O₂/Ar detonation, and the simulated cell structure compares well with the experiment results and other simulated results. Through these validations, we can conclude that the new implementation of WENO5M scheme for the simulation of chemical reacting flow based on the novel decoupled method is satisfied. Because the extension of original WENO5M scheme to calculate the chemical reacting flow based on the novel algorithm is straightforward and only minor modifications are needed, the advantages of this uncoupled algorithm is obvious.