Abstract: Atmospheric density is a fundamental parameter for vehicle designing and flight controlling. In recent years, many researchers have discovered that atmospheric densities in the upper mesosphere and lower thermosphere predicted by the empirical model, such as USSA-76 and NRLMSISE-00, are larger than the measured values. On the other hand, vehicle designing is tending to be more detailed, and engineers hope that the empirical models provide densities under variable latitudes, day-night times and seasons. Based on that, the present work analyzesdependences of near-space atmospheric density on latitude, solar local time and date, by using satellite observed data. Emphasizes are put on density fluctuation patterns and amplitudes. The fluctuation patterns caused by latitude and date vary with altitude, and the amplitudes are largest at 78 km and locally smallest at about 22 km and 92 km. The fluctuation amplitude caused by the solar local time increases monotonically with altitude. Based on the temporal-spatialfluctuationlaw, we proposed the temporal-spatial fluctuation modelfor the near-space atmospheric density, which describes the density fluctuations with latitude, local time and date. The present model describes the temporal-spatial fluctuations better than the existed empirical models at variable altitudes. The confidence coefficient of the present model is much better than NRLMSISE-00 under the same error band. The modeling method in this work is reasonable, and the obtained model could be used in near-space vehicle designing.