Abstract: Under the pressure of energy and environmental protection, the electric vehicle and intelligent driving have been attached great attention in recent years. The wheel vibration of the electric vehicle driven by hub motors is severe, which has the more interaction with the bridge pavement. Current studies are mainly aimed at traditional vehicles, while there are few works on the dynamic interaction between the electric wheels with highway bridge and the vibration of multi-vehicle-bridge coupling system based on intelligent driving fleets. In this paper, the researches are carried out based on the electric vehicle driven by hub motors. Considering the multi-point contact relationship between the wheel and bridge deck, the vehicle-bridge coupling dynamic characteristics of two intelligent driving electric vehicles driven by hub motors crossing the bridge are studied. The influences of motor mass, motor excitation, tire and suspension stiffness nonlinearity, vehicle distance and vehicle speed on vibration response of the coupling system, as well as the influences of bridge irregularities excitation and triple coupling excitation on ride comfort of the electric vehicle are analyzed. The results show that, the vehicle distance and vehicle speed are important factors which affecting the vibration characteristics of the vehicle-bridge coupling system. In the dynamic design of the vehicle-bridge coupling system, the influence of the vehicle distance and vehicle speed should be pay more attention. The more flat the bridge deck is, the more significant of influence of motor excitation and bridge deck secondary excitation on vehicle ride comfort and road friendliness are. When the vehicle is driving on a flat bridge deck, the influence of the two kinds of excitation on the hub motors electric vehicle should not be ignored. The proposed model in this paper is expected to provide a theoretical reference for the study of coupling vibration of the intelligent driving electric vehicles and bridge.